Saline-push improves rubidium-82 PET image quality.

ABSTRACT:

Introduction

Rubidium-82 (⁸²Rb) PET is used widely for myocardial perfusion imaging. The purpose of this study was to investigate if an additional saline-push following the ⁸²Rb elution improves PET image quality.

Methods

⁸²Rb PET scans were acquired with and without 26 mL saline-push in six patients as part of a clinical quality improvement program. Dynamic images were analyzed to measure the total activity delivered to the superior vena cava (SVC) and retained in the left ventricle (LV) myocardium. Tracer uptake images were used to measure blood background coefficient-of-variation (COV), myocardium-to-blood signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) to assess image quality.

Results

Similar eluted activity was meas

SUBMITTER: Renaud JM 

PROVIDER: S-EPMC6908549 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature