Long-term prognostic value of quantitative myocardial perfusion in patients with chest pain and normal coronary arteries.

ABSTRACT:

Background

Patients with chest pain and no obstructive coronary artery disease have shown a high incidence of major adverse cardiovascular events (MACE). We evaluated the role of absolute myocardial perfusion quantification in predicting all-cause mortality and MACE during long-term follow-up in this group of patients.

Methods

We studied 79 patients who underwent Nitrogen-13 ammonia PET for quantification of global myocardial blood flow (MBF) and myocardial flow reserve (MFR) due to suspected impaired myocardial perfusion. Patients with coronary artery disease (i.e., > 30% stenosis in one or more coronary arteries) were excluded. We assessed all-cause mortality and MACE. MACE was defined as the composite incidence of death, myocardial infarction (MI), or hospitalization due

SUBMITTER: Monroy-Gonzalez AG 

PROVIDER: S-EPMC6908551 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature