Changes in meta-transcriptome of rumen epimural microbial community and liver transcriptome in young calves with feed induced acidosis.

ABSTRACT: The common management practices of dairy calves leads to increased starch concentration in feed, which subsequently may cause rumen acidosis while on milk and during weaning. Until recently, few attempts were undertaken to understand the health risks of prolonged ruminal acidosis in post weaning calves. Resultantly, the molecular changes in the digestive tracts in post-weaning calves with ruminal acidosis remain largely unexplored. In this study, we investigated the liver transcriptome changes along with its correlation with the rumen microbial rRNA expression changes in young calves using our model of feed induced ruminal acidosis. In this model, new born calves were fed a highly processed, starch-rich diet starting from one week of age through 16 weeks. A total of eight calves were invol

SUBMITTER: Li W 

PROVIDER: S-EPMC6908691 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature