Association between ELP4 rs986527 polymorphism and the occurrence and development of intracranial arachnoid cyst.

ABSTRACT:

Objective

The association between ELP4 rs986527 polymorphism and the occurrence and development of intracranial arachnoid cyst was studied in this paper.

Methods

Eighty-five patients diagnosed with intracranial arachnoid cysts by cerebral computed tomography scan were selected. Sixty-three healthy volunteers for medical examination in hospitals served as controls. The cognition, depressive symptoms, and the likelihood of headache, dizziness, head trauma history, dementia, depression, and epilepsy were assessed. ELP4 genotypes and its allele frequency were determined by PCR, endonuclease restriction analysis, and gel electrophoresis.

Results

ELP4 rs986527 had three genotypes: TT, TC, and CC. The intracranial arachnoid cyst group showed no statistically significant diff

SUBMITTER: Li K 

PROVIDER: S-EPMC6908874 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature