Real-time photoacoustic assessment of radiofrequency ablation lesion formation in the left atrium.

ABSTRACT: In interventional electrophysiology, catheter-based radiofrequency (RF) ablation procedures restore cardiac heart rhythm by interrupting aberrant conduction paths. Real-time feedback on lesion formation and post-treatment lesion assessment could overcome procedural challenges related to ablation of underlying structures and lesion gaps. This study aims to evaluate real-time visualization of lesion progression and continuity during intra-atrial ablation with photoacoustic (PA) imaging, using clinically deployable technology. A PA-enabled RF ablation catheter was used to ablate and illuminate porcine left atrium, both excised and intact in a passive beating heart ex-vivo, for photoacoustic signal generation. PA signals were received with an intracardiac echography catheter. Using the ratio o

SUBMITTER: Iskander-Rizk S 

PROVIDER: S-EPMC6909067 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature