Data on a genome-wide association study of type 2 diabetes in a Maya population.

ABSTRACT: Maya communities have been shown to exhibit type 2 diabetes (T2D) with high prevalence compared with Mexican mestizo populations. Furthermore, some variants associated with the risk for T2D have been described. In this study, we describe the results of a pilot genome wide association study (GWAS) using 817,823 single nucleotide polymorphisms (SNPs) to identify candidate variants for replication in future studies. Herein, we present the GWAS study data, which were divided into three parts: first, 1289 ancestry informative markers (AIMs) were selected for Latino populations containing European, African, and Native American SNPs obtained from the literature; second, a GWAS hypothesis free to select candidate genes associated with T2D was performed, which identified 24 candidate genes; and thi

SUBMITTER: Totomoch-Serra A 

PROVIDER: S-EPMC6909262 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature