Exploring profile and potential influencers of vaginal microbiome among asymptomatic pregnant Chinese women.

ABSTRACT:

Background

This study was designed to explore the profile and potential influencers of the vaginal microbiome (VMB) among asymptomatic pregnant Chinese women and its possible association with pregnancy outcomes.

Methods

A prospective study was conducted among pregnant Chinese women receiving regular prenatal care at a hospital in Shanghai, China from March 2017 to March 2018. Vaginal swabs were obtained from 113 asymptomatic pregnant women in mid-pregnancy and sequenced by the V3-V4 region of 16S rRNA on an Ion S5™ XL platform. Demographic characteristics and major pregnancy outcomes were collected through questionnaires and electronic medical records.

Results

The predominant vaginal community state types (CSTs) were CST I (45.1%) and CST III (31.9%). Participants wer

SUBMITTER: He Y 

PROVIDER: S-EPMC6910115 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature