High Expression of TTYH3 is Related to Poor Clinical Outcomes in Human Gastric Cancer.

ABSTRACT: Ion channels play important roles in regulating various cellular processes and malignant transformation. Expressions of some chloride channels have been suggested to be associated with patient survival in gastric cancer (GC). However, little is known about the expression and function of TTYH3, a gene encoding a chloride ion channel, in cancer progression. Here, we comprehensively analyzed the expression of TTYH3 and its clinical outcome in GC using publicly available cancer gene expression and patient survival data through various databases. We examined the differences of TTYH3 expression between cancers and their normal tissues using the Oncomine, UALCAN, and GEO (Gene Expression Omnibus) databases. TTYH3 expression was investigated from immunohistochemistry images using the Human Protein

SUBMITTER: Saha SK 

PROVIDER: S-EPMC6912211 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature