Ontology highlight
ABSTRACT:
SUBMITTER: Moon S
PROVIDER: S-EPMC6912341 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Moon Sohee S Shin Dong Wun DW Kim Sujin S Lee Young-Sun YS Mankhong Sakulrat S Yang Seong Wook SW Lee Phil Hyu PH Park Dong-Ho DH Kwak Hyo-Bum HB Lee Jae-Sun JS Kang Ju-Hee JH
Journal of clinical medicine 20191115 11
Exosome-like extracellular vesicles (ELVs) contain biomolecules that have potential as diagnostic biomarkers, such as proteins, micro-RNAs (miRNAs), and lipids. However, it is difficult to enrich ELVs consistently with high yield and purity from clinical samples, which hampers the development of ELV biomarkers. This is particularly true for miRNAs in protein-rich plasma. Hence, we modified ELV isolation protocols of three commercially available polymer-precipitation-based kits using proteinase K ...[more]