C-Reactive Protein and Neutrophil/Lymphocytes Ratio: Prognostic Indicator for Doubling overall survival Prediction in Pancreatic Cancer Patients.

ABSTRACT: : Background: Despite modern chemotherapy regimens, survival of patients with locally advanced/metastatic pancreatic cancer remains dismal. Long-term survivors are rare and there are no prognostic scores to identify patients benefitting most from chemotherapy. This retrospective study includes 240 patients with pancreatic cancer who were treated in a primary palliative setting between the years 2007 to 2016 in a single academic institution. Survival rates were analyzed using the Kaplan-Meier method. Prognostic models including laboratory and clinical parameters were calculated using Cox proportional models in univariate and multivariate analyses. Median age at diagnosis was 67 years (range 29-90 years), 52% were female and a majority had an ECOG performance status of 0 or 1. Locally advanc

SUBMITTER: Schlick K 

PROVIDER: S-EPMC6912559 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature