Prognostic value of perioperative NT-proBNP after corrective surgery for pediatric congenital heart defects.

ABSTRACT:

Background

It is critically important to assess the prognostic value of NT-proBNP in the form of repeated measures among children undergoing surgery for congenital heart defects (CHD). The aim of the present study is to assess the value of repeated perioperative NT-proBNP in evaluating the time dependent and temporal trajectory in prognostics diagnosis during the perioperative period in a large series of children with CHD.

Methods

Repeated measures of NT-proBNP from 329 consecutive children with CHD were obtained before and 1, 12, and 36 h after surgery, respectively. For fully utilizing longitudinal characteristics, we employed parallel cross-sectional logistic regression, a two stage mixed effect model and trajectories over time analysis to mine the predictive value of per

SUBMITTER: Lin F 

PROVIDER: S-EPMC6913023 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature