A systematic review and meta-analysis of antibiotic prophylaxis in skin graft surgery: A protocol.

ABSTRACT:

Introduction

There is little evidence-based guidance on the use of prophylactic antibiotics in skin surgery; whilst antibiotics may protect against surgical site infections (SSI), they have associated side effects, increase the risk of adverse events, and can propagate antibiotic resistance. We present a protocol for a systematic review to establish whether the benefit of prophylactic antibiotics overrides the risk, for patients undergoing autograft surgery.

Methods

The systematic review will be registered a priori on researchregistry.com and will be conducted in line with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA). A search strategy will be devised to investigate 'skin graft surgery and use of antibiotics'. The following electronic datab

SUBMITTER: Borrelli MR 

PROVIDER: S-EPMC6913549 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature