Fluoride exposure from infant formula and child IQ in a Canadian birth cohort.

ABSTRACT:

Background

Infant consumption of formula reconstituted with fluoridated water can lead to excessive fluoride intake. We examined the association between fluoride exposure in infancy and intellectual ability in children who lived in fluoridated or non-fluoridated cities in Canada.

Methods

We examined 398 mother-child dyads in the Maternal-Infant Research on Environmental Chemicals cohort who reported drinking tap water. We estimated water fluoride concentration using municipal water reports. We used linear regression to analyze the association between fluoride exposure and IQ scores, measured by the Wechsler Primary and Preschool Scale of Intelligence-III at 3-4 years. We examined whether feeding status (breast-fed versus formula-fed) modified the impact of water fluoride and

SUBMITTER: Till C 

PROVIDER: S-EPMC6913880 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature