Identification of Key Candidate Genes in Dairy Cow in Response to Escherichia coli Mastitis by Bioinformatical Analysis.

ABSTRACT: At present, bovine mastitis is one of the most costly diseases affecting animal health and welfare. Escherichia coli (E. coli) is considered to be one of the main pathogens causing mastitis with clinical signs in dairy cattle. However, the cure rate of E. coli mastitis is low, and the pathogenesis of E. coli mastitis is not completely known. In order to develop new strategies for the rapid detection of E. coli mastitis, a comprehensive molecular investigation of E. coli mastitis is necessary. Hence, this study integrated three microarray data sets to identify the potential key candidate genes in dairy cow in response to E. coli mastitis. Differentially expressed genes (DEGs) were screened in mammary gland tissues with live E. coli inf

SUBMITTER: Li L 

PROVIDER: S-EPMC6915111 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature