Dietary antioxidative supplements and diabetic retinopathy; a systematic review.

ABSTRACT:

Purpose

There is controversial data regarding the effects of dietary antioxidative supplements on diabetic retinopathy (DR). We conducted a systematic review of both observational and randomized controlled clinical trials (RCTs) to clarify whether they are effective or not.

Methods

All observational and RCTs conducted by antioxidative supplements on DR published up to 1 January 2018 in PubMed, Web of Sciences, Scopus and Cochrane Library databases were included. Exclusion criteria were animal studies, and studies conducted in Type 1 diabetes mellitus (T1DM), children or pregnant women. Main outcome measures were reporting the incidence or progression of DR in T2DM by assessment of visual fields, and measurements of oxidative and antioxidative biomarkers. The quality of repor

SUBMITTER: Tabatabaei-Malazy O 

PROVIDER: S-EPMC6915253 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature