New hemostatic device for grade IV-V liver injury in porcine model: a proof of concept.

ABSTRACT: Background:The liver is the most injured organ following abdominal trauma. Uncontrolled bleeding remains the main cause of early liver injury-related death, with a mortality rate of 50-54% in the first 24 h after admission and with 80% of operative deaths. Packing and reoperation account for the increased survival in severe liver trauma, and they are recommended for severe liver injuries (grades IV-V).Perihepatic packing can lead to several potential complications. An excessive packing can cause complications due to abdominal compartment syndrome, while a soft packing may be ineffective, and thus, bleeding can continue inadvertently with the consequent hypovolemic shock and potentially death. Methods:We designed a new vacuum-based device to perform perihepatic packing without the negative

SUBMITTER: Segura-Sampedro JJ 

PROVIDER: S-EPMC6916102 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature