Impact of therapeutic hypothermia on infantile spasms: an observational cohort study.

ABSTRACT:

Aim

To establish the incidence of infantile spasms in children in the southern region of the Republic of Ireland and to compare the incidence of infantile spasms before and after the introduction of therapeutic hypothermia in infants with hypoxic-ischemic encephalopathy (HIE).

Method

Children born between 2003 and 2015 and diagnosed with infantile spasms (epileptic spasms with or without hypsarrhythmia) in the first 2 years of life were identified through audits of electroencephalography reports and paediatric neurology patient lists. Data on live births were obtained from the regional hospital statistics databases. Medical charts of infantile spasm cases were reviewed for demographic information, diagnostic workup results, treatment response, disease course, and development

SUBMITTER: Abu Dhais F 

PROVIDER: S-EPMC6916151 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature