HprK_Xcc is a serine kinase that regulates virulence in the Gram-negative phytopathogen Xanthomonas campestris.

ABSTRACT: The HprK serine kinase is a component of the phosphoenolpyruvate phosphotransferase system (PTS) of bacteria that generally regulates catabolite repression through phosphorylation/dephosphorylation of the PTS protein PtsH at a conserved serine residue. However, many bacteria do not encode a complete PTS or even have an HprK homologue. Xanthomonas campestris pv. campestris (Xcc) is a pathogen that cause black rot disease in crucifer plants and one of the few Gram-negative bacteria that encodes a homologue of HprK protein (herein HprK_Xcc ). To gain insight into the role of HprK_Xcc and other PTS-related components in Xcc we individually mutated and phenotypically assessed the resulting strains. Deletion of hprK _Xcc demonstrated its requirement for virulence an

SUBMITTER: Li RF 

PROVIDER: S-EPMC6916182 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature