Impact of national influenza vaccination strategy in severe influenza outcomes among the high-risk Portuguese population.

ABSTRACT:

Background

All aged individuals with a chronic condition and those with 65 and more years are at increased risk of severe influenza post-infection complications. There is limited research on cases averted by the yearly vaccination programs in high-risk individuals. The objective was to estimate the impact of trivalent seasonal influenza vaccination on averted hospitalizations and death among the high-risk population in Portugal.

Methods

The impact of trivalent seasonal influenza vaccination was estimated using vaccine coverage, vaccine effectiveness and the number of influenza-related hospitalizations and deaths. The number of averted events (NAE), prevented fraction (PF) and number needed to vaccinate (NVN) were estimated for seasons 2014/15 to 2016/17.

Results

The v

SUBMITTER: Machado A 

PROVIDER: S-EPMC6916191 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature