Technical Note: Ontology-guided radiomics analysis workflow (O-RAW).

ABSTRACT: PURPOSE:Radiomics is the process to automate tumor feature extraction from medical images. This has shown potential for quantifying the tumor phenotype and predicting treatment response. The three major challenges of radiomics research and clinical adoption are: (a) lack of standardized methodology for radiomics analyses, (b) lack of a universal lexicon to denote features that are semantically equivalent, and (c) lists of feature values alone do not sufficiently capture the details of feature extraction that might nonetheless strongly affect feature values (e.g. image normalization or interpolation parameters). These barriers hamper multicenter validation studies applying subtly different imaging protocols, preprocessing steps and radiomics software. We propose an open-source ontology-guid

SUBMITTER: Shi Z 

PROVIDER: S-EPMC6916323 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature