Update on treatments for nonmotor symptoms of Parkinson's disease-an evidence-based medicine review.

ABSTRACT:

Objective

To update evidence-based medicine recommendations for treating nonmotor symptoms in Parkinson's disease (PD).

Background

The International Parkinson and Movement Disorder Society Evidence-Based Medicine Committee's recommendations for treatments of PD were first published in 2002, updated in 2011, and now updated again through December 31, 2016.

Methods

Level I studies testing pharmacological, surgical, or nonpharmacological interventions for the treatment of nonmotor symptoms in PD were reviewed. Criteria for inclusion and quality scoring were as previously reported. The disorders covered were a range of neuropsychiatric symptoms, autonomic dysfunction, disorders of sleep and wakefulness, pain, fatigue, impaired olfaction, and ophthalmologic dysfunction. Cl

SUBMITTER: Seppi K 

PROVIDER: S-EPMC6916382 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature