Association between contact sports participation and chronic traumatic encephalopathy: a retrospective cohort study.

ABSTRACT: Chronic traumatic encephalopathy is a debilitating neurodegenerative disorder associated with repetitive traumatic brain injuries often sustained through prior contact sport participation. The frequency of this disorder in a diverse population, including amateur athletes, is unknown. Primary historical obituary and yearbook records were queried for 2566 autopsy cases in the Mayo Clinic Tissue Registry resulting in identification of 300 former athletes and 450 non-athletes. In these cases, neocortical tissue was screened for tau pathology with immunohistochemistry, including pathology consistent with chronic traumatic encephalopathy, blinded to exposure or demographic information. Using research infrastructure of the Rochester Epidemiology Project, a comprehensive and established medical re

SUBMITTER: Bieniek KF 

PROVIDER: S-EPMC6916416 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature