Imaging of subendocardial adipose tissue and fiber orientation distributions in the human left atrium using optical coherence tomography.

ABSTRACT:

Background

Optical coherence tomography (OCT) has the potential to provide real-time imaging guidance for atrial fibrillation ablation, with promising results for lesion monitoring. OCT can also offer high-resolution imaging of tissue composition, but there is insufficient cardiac OCT data to inform the use of OCT to reveal important tissue architecture of the human left atrium. Thus, the objective of this study was to define OCT imaging data throughout the human left atrium, focusing on the distribution of adipose tissue and fiber orientation as seen from the endocardium.

Methods and results

Human hearts (n = 7) were acquired for imaging the left atrium with OCT. A spectral-domain OCT system with 1325 nm center wavelength, 6.5 μm axial resolution, 15 μm lateral resolution,

SUBMITTER: Lye TH 

PROVIDER: S-EPMC6916589 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature