Heated Intravesical Chemotherapy: Biology and Clinical Utility.

ABSTRACT: Non-muscle-invasive bladder cancer can be a challenging disease to manage. In recent years, hyperthermia therapy in conjunction with intravesical therapy has been gaining traction as a treatment option for bladder cancer, especially if Bacillus Calmette-Guerin might not be available. Trials of intravesical chemotherapy with heat are few and there has been considerable heterogeneity between studies. However, multiple new trials have accrued and high-quality data are forthcoming. In this review, we discuss the role of combined intravesical hyperthermia and chemotherapy as a novel approach for the treatment of bladder cancer.

SUBMITTER: Tan WP 

PROVIDER: S-EPMC6917042 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature