Smoking trajectories and risk of stroke until age of 50 years - The Northern Finland Birth Cohort 1966.

ABSTRACT:

Background

Smoking is a well-known risk factor for stroke. However, the relationship between smoking trajectories during the life course and stroke is not known.

Aims

We aimed to study the association of smoking trajectories and smoked pack-years with risk of ischemic and haemorrhagic strokes in a population-based birth cohort followed up to 50 years of age.

Methods

Within the Northern Finland Birth Cohort 1966, 11,999 persons were followed from antenatal period to age 50 years. The smoking behaviour was assessed with postal questionnaires at ages 14, 31 and 46 years. Stroke diagnoses were collected from nationwide registers using unique study number linkage. The associations between smoking behaviour and stroke risk were estimated using Cox regression models.

Resu

SUBMITTER: Rissanen I 

PROVIDER: S-EPMC6917292 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature