Accessing 1,2-Substituted Cyclobutanes through 1,2-Azaborine Photoisomerization.

ABSTRACT: We provide a seminal example of the utility of the 1,2-azaborine motif as a 4C+1N+1B synthon in organic synthesis. Specifically, conditions for the practically scalable photoisomerization of 1,2-azaborine in a flow reactor are reported that furnish aminoborylated cyclobutane derivatives. The C-B bonds could also be functionalized to furnish a diverse set of highly substituted cyclobutanes.

SUBMITTER: Giustra ZX 

PROVIDER: S-EPMC6917847 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature