A Case study on the utility of predictive toxicology tools in alternatives assessments for hazardous chemicals in children's consumer products.

ABSTRACT: Children's consumer products represent an important exposure source for many toxicants. Chemicals of high concern, as designated by the Washington State Child Safe Product Act include phthalates, Bisphenol A (BPA) and parabens, among others. As regulation and reporting requirements increase, so has demand for safer alternatives. This project examines how predictive toxicology and exposure comparison tools can fill gaps in alternatives assessments for hazardous chemicals found in children's products. Phthalates, parabens, BPA and their alternatives were assessed for endocrine disruption and reproductive toxicity using authoritative lists and US Environmental Protection Agency's (EPA) predictive toxicology and exposure comparison tools. Resources included the European Chemical Agency's Endoc

SUBMITTER: Smith MN 

PROVIDER: S-EPMC6917906 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature