A simulation study of the influence of the traveling wave patterns on ion mobility separations in structures for lossless ion manipulations.

ABSTRACT: Probing molecular properties in the gas phase requires the integration of complementary ion manipulation approaches such as ion mobility spectrometry. Structures for lossless ion manipulations (SLIM) have recently been developed to perform ultra-high resolution ion mobility separations using traveling waves as well as providing other advanced capabilities. Despite its success, the design aspects of SLIM have not been fully explored and remained largely unchanged. Here, we report on a computational study using SIMION simulations of a number of traveling wave (TW) patterns that can be used in SLIM. The TW pattern used in the current SLIM device is a set of 8 electrodes where, at any time, 4 electrodes are held at high voltage (i.e., 1111), while the other 4 electrodes are held at low voltage

SUBMITTER: Li A 

PROVIDER: S-EPMC6917922 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature