Identifying metabolomic profiles of inflammatory diets in postmenopausal women.

ABSTRACT:

Background

We previously showed that a food-based empirical dietary inflammatory pattern (EDIP) score is associated with circulating inflammatory biomarkers. Metabolomic profiling of inflammatory diets may therefore provide insights on mechanisms contributing to disease etiology and prognosis. We aimed to elucidate metabolites associated with inflammatory diets among postmenopausal women, utilizing a robust study design that incorporates independent discovery and validation datasets.

Methods

This baseline cross-sectional investigation evaluated associations between continuous EDIP scores calculated from food frequency questionnaires and 448 log-transformed plasma metabolites as outcomes in multivariable-adjusted linear regression analyses. Metabolites were measured with liqu

SUBMITTER: Tabung FK 

PROVIDER: S-EPMC6918009 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature