Can the optimal cervical length for placing ultrasound-indicated cerclage be identified?

ABSTRACT:

Objective

To assess a continuum of cervical length (CL) cut-offs for the efficacy of ultrasound-indicated cerclage in women with previous spontaneous preterm birth (PTB).

Methods

This was a planned secondary analysis of a multicenter randomized clinical trial of ultrasound-indicated cerclage for the prevention of PTB in high-risk women. The efficacy of cerclage for preventing recurrent PTB < 35, < 32 and < 24 weeks' gestation was assessed using multivariable logistic regression analysis. Odds ratios (ORs) and CIs were estimated for a range of CL cut-offs using bootstrap regression. The 2.5(th) and 97.5(th) percentiles of bootstrapped ORs determined the CIs. Results were illustrated using smoothed curves superimposed on estimated ORs by CL cut-off.

Results

Of 301 women

SUBMITTER: Szychowski JM 

PROVIDER: S-EPMC6918708 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature