Olfactory bulb volume changes associated with trans-sphenoidal pituitary surgery.

ABSTRACT:

Objective

The trans-sphenoidal approach is most frequently used for pituitary adenoma (PA) enucleation. However, effects of this surgery on neighboring structures have received little attention so far. In particular, no investigations on olfactory bulb (OB) anatomy after trans-sphenoidal surgery have been reported. Because impairment of olfaction has been shown in small groups following trans-sphenoidal surgery we hypothesized that the transnasal approach is likely to alter OB volume which is associated with changes of olfactory function.

Methods

The study comprised 33 patients with pituitary adenoma (14 women and 19 men, mean age 50 years). Comprehensive assessment of olfactory function was conducted with the "Sniffin' Sticks" test kit. Based on magnetic resonance imaging s

SUBMITTER: Podlesek D 

PROVIDER: S-EPMC6919594 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature