Adverse drug reactions in drug information databases: does presentation affect interpretation?

ABSTRACT:

Objective

Formatting of adverse drug reaction (ADR) information differs among drug information (DI) resources and may impact clinical decision-making. The objective of this study was to determine whether ADR formatting impacts adverse event interpretation by pharmacy practitioners and students.

Methods

Participants were randomized to receive ADR information in a comparative quantitative (CQUANT), noncomparative quantitative (NQUANT), or noncomparative qualitative (NQUAL) format to interpret 3 clinical vignettes. Vignettes involved patients presenting with adverse events that varied in the extent to which they were associated with a medication. The primary outcome was interpretation of the likelihood of medication-induced adverse events on a 10-point Likert scale. Lower scori

SUBMITTER: McConachie SM 

PROVIDER: S-EPMC6919994 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature