Molecular Docking Studies of a Cyclic Octapeptide-Cyclosaplin from Sandalwood.

ABSTRACT: Natural products from plants, such as chemopreventive agents, attract huge attention because of their low toxicity and high specificity. The rational drug design in combination with structure-based modeling and rapid screening methods offer significant potential for identifying and developing lead anticancer molecules. Thus, the molecular docking method plays an important role in screening a large set of molecules based on their free binding energies and proposes structural hypotheses of how the molecules can inhibit the target. Several peptide-based therapeutics have been developed to combat several health disorders, including cancers, metabolic disorders, heart-related diseases, and infectious diseases. Despite the discovery of hundreds of such therapeutic peptides however, only few pept

SUBMITTER: Mishra A 

PROVIDER: S-EPMC6920920 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature