Comparative Proteomic Analysis Reveals Immune Competence in Hemolymph of Bombyx mori Pupa Parasitized by Silkworm Maggot Exoristasorbillans.

ABSTRACT: The silkworm maggot, Exoristasorbillans, is a well-known larval endoparasitoid of the silkworm Bombyxmori that causes considerable damage to the silkworm cocoon crop. To gain insights into the response mechanism of the silkworm at the protein level, we applied a comparative proteomic approach to investigate proteomic differences in the hemolymph of the female silkworm pupae parasitized by E. sorbillans. In total, 50 differentially expressed proteins (DEPs) were successfully identified, of which 36 proteins were upregulated and 14 proteins were downregulated in response to parasitoid infection. These proteins are mainly involved in disease, energy metabolism, signaling pathways, and amino acid metabolism. Eight innate immune proteins were distinctly upregulated to resist maggot parasitism.

SUBMITTER: Xu PZ 

PROVIDER: S-EPMC6920964 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature