Population-averaged atlas of the macroscale human structural connectome and its network topology.

ABSTRACT: A comprehensive map of the structural connectome in the human brain has been a coveted resource for understanding macroscopic brain networks. Here we report an expert-vetted, population-averaged atlas of the structural connectome derived from diffusion MRI data (N = 842). This was achieved by creating a high-resolution template of diffusion patterns averaged across individual subjects and using tractography to generate 550,000 trajectories of representative white matter fascicles annotated by 80 anatomical labels. The trajectories were subsequently clustered and labeled by a team of experienced neuroanatomists in order to conform to prior neuroanatomical knowledge. A multi-level network topology was then described using whole-brain connectograms, with subdivisions of the association pathwa

SUBMITTER: Yeh FC 

PROVIDER: S-EPMC6921501 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature