Premature deaths by visceral leishmaniasis in Brazil investigated through a cohort study: A challenging opportunity?

ABSTRACT:

Background

Visceral Leishmaniasis (VL) is the most severe form of leishmaniasis because it can lead to death. In the Americas, 96% of cases are in Brazil, and despite efforts, the fatality rate has increased in the past years. We analyzed deaths associated to VL in Brazil and investigated the factors that could influence on the timeliness of fatal outcome with emphasis on time (tStoD).

Methodology

The registered deaths by VL were sourced from the Brazilian National Notification System from 2007-2014. Through a retrospective cohort study, univariate and multivariable Cox proportional hazards model analysis were performed and investigated the factors that could influence the time (tStoD). These factors were analyzed through survival models.

Results

Out of the 1,589 repo

SUBMITTER: Maia-Elkhoury ANS 

PROVIDER: S-EPMC6922316 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature