MicrIO: an open-source autosampler and fraction collector for automated microfluidic input-output.

ABSTRACT: Microfluidic devices are an enabling technology for many labs, facilitating a wide range of applications spanning high-throughput encapsulation, molecular separations, and long-term cell culture. In many cases, however, their utility is limited by a 'world-to-chip' barrier that makes it difficult to serially interface samples with these devices. As a result, many researchers are forced to rely on low-throughput, manual approaches for managing device input and output (IO) of samples, reagents, and effluent. Here, we present a hardware-software platform for automated microfluidic IO (micrIO). The platform, which is uniquely compatible with positive-pressure microfluidics, comprises an 'AutoSipper' for input and a 'Fraction Collector' for output. To facilitate widespread adoption, both are op

SUBMITTER: Longwell SA 

PROVIDER: S-EPMC6923132 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature