Comparative measurement of FeLV load in hemolymphatic tissues of cats with hematologic cytopenias.

ABSTRACT:

Background

Feline leukemia virus (FeLV) is a serious viral infection in cats. FeLV is found in some tissues, such as spleen, lymph nodes and epithelial tissues. However, there is controversy about the organ in which the virus can be reliably detected in infected cats. The purpose of this study was to determine the level of viral infection in hemolymphatic tissues, including blood, bone marrow and spleen by reverse-transcriptase quantitative polymerase chain reaction (RT-qPCR).

Results

A total of 31 cats with clinical signs of FeLV infection associated with at least a single lineage hematologic cytopenia were included in this study. Peripheral blood, bone marrow and spleen samples were obtained from each cat. Complete blood counts, biochemical tests, and a rapid test to detec

SUBMITTER: Abdollahi-Pirbazari M 

PROVIDER: S-EPMC6924046 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature