Neutral genomic signatures of host-parasite coevolution.

ABSTRACT:

Background

Coevolution is a selective process of reciprocal adaptation in hosts and parasites or in mutualistic symbionts. Classic population genetics theory predicts the signatures of selection at the interacting loci of both species, but not the neutral genome-wide polymorphism patterns. To bridge this gap, we build an eco-evolutionary model, where neutral genomic changes over time are driven by a single selected locus in hosts and parasites via a simple biallelic gene-for-gene or matching-allele interaction. This coevolutionary process may lead to cyclic changes in the sizes of the interacting populations.

Results

We investigate if and when these changes can be observed in the site frequency spectrum of neutral polymorphisms from host and parasite full genome data. We sho

SUBMITTER: Zivkovic D 

PROVIDER: S-EPMC6924072 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature