Vortioxetine treatment for generalised anxiety disorder: a meta-analysis of anxiety, quality of life and safety outcomes.

ABSTRACT:

Objectives

The aim of this study was to investigate the efficacy, tolerability, safety, and impact on quality of life (QoL) and functional status of vortioxetine treatment for patients with generalised anxiety disorder (GAD) by performing a meta-analysis of randomised controlled trials (RCTs).

Design

Systematic review and meta-analysis.

Data sources

Data mining was conducted in January 2019 across PubMed, EMBASE, PsycINFO, Cochrane Central Register of Controlled Trials Cochrane Library, Web of science and ClinicalTrials.gov.

Eligibility criteria for selecting studies

All published RCTs, which assessed the effect of vortioxetine treatment for patients with GAD when compared with a placebo group, were included.

Data extraction and synthesis

Relevant data w

SUBMITTER: Qin B 

PROVIDER: S-EPMC6924794 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature