Effect of polycystic ovary syndrome on cardiac autonomic function at a late fertile age: a prospective Northern Finland Birth Cohort 1966 study.

ABSTRACT:

Objectives

Previous studies of women in their 20s and 30s have reported impaired autonomic function in women with polycystic ovary syndrome (PCOS). We aimed to study, for the first time, whether PCOS is associated with impaired cardiac autonomic function independent of metabolic and hormonal status in their late reproductive years.

Design

A prospective Northern Finland Birth Cohort 1966 (NFBC1966) study including 5889 women born in 1966 and followed through the age of 46. At that age, n=3706/5123 women (72%) answered the postal questionnaires and n=3280/5123 women (64%) participated in the clinical examination.

Setting

General community.

Participants

The sample included women presenting both irregular menses (oligomenorrhoea or amenorrhoea) and hirsutism at age

SUBMITTER: Ollila MM 

PROVIDER: S-EPMC6924836 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature