FLUORESCENCE LIFETIME PATTERNS IN MACULAR TELANGIECTASIA TYPE 2.

ABSTRACT:

Purpose

Type 2 idiopathic macular telangiectasia (MacTel) is a rare bilateral neurodegenerative disease characterized by alterations in the macular capillary network leading to central vision loss. The purpose of this study was to quantify disease-specific retinal fluorescence lifetime patterns in patients with MacTel using fluorescence lifetime imaging ophthalmoscopy.

Participants

Both eyes of 14 patients (mean age ± SEM, 67.8 ± 6.4 years) with a clinical diagnosis of MacTel Type 2 and 14 healthy age-matched controls (age 69.8 ± 6.4 years) were included in this study.

Methods

All participants were imaged with a fluorescence lifetime imaging ophthalmoscope (Heidelberg Engineering, Germany). Mean retinal fluorescence lifetimes (Tm) were obtained in the short spectral c

SUBMITTER: Solberg Y 

PROVIDER: S-EPMC6924947 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature