WormBot, an open-source robotics platform for survival and behavior analysis in C. elegans.

ABSTRACT: Caenorhabditis elegans is a popular organism for aging research owing to its highly conserved molecular pathways, short lifespan, small size, and extensive genetic and reverse genetic resources. Here we describe the WormBot, an open-source robotic image capture platform capable of conducting 144 parallel C. elegans survival and behavioral phenotyping experiments. The WormBot uses standard 12-well tissue culture plates suitable for solid agar media and is built from commercially available robotics hardware. The WormBot is controlled by a web-based interface allowing control and monitoring of experiments from any internet connected device. The standard WormBot hardware features the ability to take both time-lapse bright field images and real-time video micrographs, allowing investigators to

SUBMITTER: Pitt JN 

PROVIDER: S-EPMC6925079 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature