Comparison of Japanese and Indian intestinal microbiota shows diet-dependent interaction between bacteria and fungi.

ABSTRACT: The bacterial species living in the gut mediate many aspects of biological processes such as nutrition and activation of adaptive immunity. In addition, commensal fungi residing in the intestine also influence host health. Although the interaction of bacterium and fungus has been shown, its precise mechanism during colonization of the human intestine remains largely unknown. Here, we show interaction between bacterial and fungal species for utilization of dietary components driving their efficient growth in the intestine. Next generation sequencing of fecal samples from Japanese and Indian adults revealed differential patterns of bacterial and fungal composition. In particular, Indians, who consume more plant polysaccharides than Japanese, harbored increased numbers of Prevotella an

SUBMITTER: Pareek S 

PROVIDER: S-EPMC6925221 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature