Pay attention to the basal ganglia: a volumetric study in early dementia with Lewy bodies.

ABSTRACT:

Background

Cortical and subcortical cognitive impairments are usually found in dementia with Lewy bodies (DLB). Roughly, they comprise visuo-constructive/executive function and attention/processing speed impairments, whereas memory would remain relatively spared. In this study, we focused on the neuro-anatomical substrates of attention and processing speed, which is still poorly understood. For the purpose of the study, we examined the correlations between behavioral scores measuring the speed of processing and the degree of cerebral atrophy in patients with prodromal to moderate DLB.

Methods

Ninety-three prodromal to moderate DLB patients (mean MMSE = 25.5) were selected to participate in the study as well as 28 healthy elderly subjects (mean MMSE = 28.9), matched in terms

SUBMITTER: Botzung A 

PROVIDER: S-EPMC6925479 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature