Five-year oncological outcome after a single fraction of accelerated partial breast irradiation in the elderly.

ABSTRACT:

Background

To update the clinical outcome of an elderly women cohort with early breast cancer who underwent accelerated partial breast irradiation (APBI) based on a post-operative single fraction of multicatheter interstitial high dose-rate brachytherapy (MIB).

Material and methods

A single institution retrospective cohort study was performed focusing on elderly patients (≥ 65 years old) presenting a low-risk breast carcinoma treated by lumpectomy plus axillary evaluation followed by MIB APBI. A single fraction of 16 Gy was prescribed on the 100% isodose. Clinical outcome at 5 years was reported based on local relapse free survival (LRFS), specific survival (SS) and overall survival (OS). Late toxicity was evaluated. Cosmetic results were evaluated clinically by the physicia

SUBMITTER: Kinj R 

PROVIDER: S-EPMC6925849 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature