Ontology highlight
ABSTRACT:
SUBMITTER: Shimobayashi SF
PROVIDER: S-EPMC6925986 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Shimobayashi Shunsuke F SF Ohsaki Yuki Y
Proceedings of the National Academy of Sciences of the United States of America 20191126 51
Lipid droplets are cytoplasmic microscale organelles involved in energy homeostasis and handling of cellular lipids and proteins. The core structure is mainly composed of two kinds of neutral lipids, triglycerides and cholesteryl esters, which are coated by a phospholipid monolayer and proteins. Despite the liquid crystalline nature of cholesteryl esters, the connection between the lipid composition and physical states is poorly understood. Here, we present a universal intracellular phase diagra ...[more]