Inter-laboratory proficiency testing scheme for tumour next-generation sequencing in Ontario: a pilot study.

ABSTRACT:

Background

A pilot inter-laboratory proficiency scheme for 5 Ontario clinical laboratories testing tumour samples for the Ontario-wide Cancer Targeted Nucleic Acid Evaluation (octane) study was undertaken to assess proficiency in the identification and reporting of next-generation sequencing (ngs) test results in solid tumour testing from archival formalin-fixed, paraffin-embedded (ffpe) tissue.

Methods

One laboratory served as the reference centre and provided samples to 4 participating laboratories. An analyte-based approach was applied: each participating laboratory received 10 ffpe tissue specimens profiled at the reference centre, with tumour site and histology provided. Laboratories performed testing per their standard ngs tumour test protocols. Items returned for asse

SUBMITTER: Spence T 

PROVIDER: S-EPMC6927773 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature