FluChip-8G Insight: HA and NA subtyping of potentially pandemic influenza A viruses in a single assay.

ABSTRACT:

Background

Global influenza surveillance in humans and animals is a critical component of pandemic preparedness. The FluChip-8G Insight assay was developed to subtype both seasonal and potentially pandemic influenza viruses in a single assay with a same day result. FluChip-8G Insight uses whole gene segment RT-PCR-based amplification to provide robustness against genetic drift and subsequent microarray detection with artificial neural network-based data interpretation.

Objectives

The objective of this study was to verify and validate the performance of the FluChip-8G Insight assay for the detection and positive identification of human and animal origin non-seasonal influenza A specimens.

Methods

We evaluated the ability of the FluChip-8G Insight technology to type and

SUBMITTER: Toth E 

PROVIDER: S-EPMC6928037 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature