Curcumin use in ulcerative colitis: is it ready for prime time? A systematic review and meta-analysis of clinical trials.

ABSTRACT:

Background

Curcumin, an active ingredient of the Indian herb turmeric (Curcuma longa), has shown promising anti-inflammatory properties. Studies of its potential benefits in treating patients with ulcerative colitis (UC) are limited. We performed a systematic review and meta-analysis of human randomized placebo controlled trials to evaluate the efficacy of adjunctive therapy with curcumin in treating patients with UC.

Methods

We conducted a search of several databases (from January 2000 to September 2018). A random-effects model was used for analysis. We assessed heterogeneity between study-specific estimates using the Cochran Q statistical test, 95% prediction interval (PI) and I² statistics. The outcomes assessed were the pooled odds of clinical response and rem

SUBMITTER: Chandan S 

PROVIDER: S-EPMC6928475 | biostudies-literature | 2020 Jan-Feb

REPOSITORIES: biostudies-literature